Initially, cells are dissociated from liver tissues into single-cell suspensions using in vivo enzymatic perfusion or ex vivo digestion methods. The cells of interest are then enriched from the ...

Advances in next-generation sequencing (NGS) technologies have lowered costs and reduced the complexity of DNA and RNA sequencing, enabling new possibilities when studying gene activity. In ...

Researchers used spatial transcriptomics to map gene expression in developing wheat spikes at single-cell resolution.

Spatial transcriptomics (ST) technologies reveal the spatial organization of gene expression in tissues, providing critical insights into development, neurobiology, and cancer. However, the high cost ...

Researchers have developed two innovative tools to help us delve deeper into cell communication, offering spatial insight ...

T cells sit at the center of modern immunotherapy, yet many of the rules that govern their activation, differentiation, dysfunction (e.g., exhaustion), and ...

Type 2 diabetes (T2D) is a major chronic metabolic disease worldwide and is especially prevalent in older adults. Although many synthetic drugs are ...