Pilot trials have a key role in preparing for definitive randomized trials, yet determining their sample size remains a common challenge. This article provides practical guidance, methods, and ...

1 Department of Epidemiology, University of North Carolina Gillings School of Global Public Health, Chapel Hill, NC 27599, USA 2 Department of Psychiatry, Washington University School of Medicine, St ...

This script aims to compute the sample size for the bioequivalence trials from pivotal bioequivalence trials. The calculation takes into account the design, the coefficient of variation (CV) and the ...

Define statistical power List the potential consequences of doing a study that has low power, and also a study that has too much power. Explain what a type 1 and type ...

Power analyses and sample size calculations are important parts of many research projects. Often, before data are even collected, it is necessary to calculate and justify the required sample size for ...